MYHEP DVIR
DESCRIPTION:
Drug profile :Myhep dvir tablet, a combination of two most effective anti-viral agents called as Sofosbuvir & Daclatasvir. This tablet is most effective against serious condition like hepatitis C viral infection induced by genotype I or III.
Myhep dvir tablet is the merger of two non structural proteins like NS5A & NS5B inhibitors.
This phosphoprotein is important for viral production.
Myhep dvir tablets are used as single dose therapy, which is most efficient for treating the hepatitis condition.
Prescribing information :
For the most part Daclatasvir is utilized as a part of mix with sofosbuvir for better against viral action.
In decompensated cirrhosis condition, Myhep dvir tablet ought to be utilized simultaneously with ribavirin
Mechanism:
After oral confirmation of Myhep dvir tablets, it might experience some structure for showing the counter pervasive action.
Myhep dvir: Sofosbuvir and Daclatasvir
Dosage regimens
On the basis of body weight of the patients the dose of ribavirin should be calculated.
An starting dose of ribavirin is 600mg as once daily, followed by increasing the dose to 1000mg.
ü < 75kg of body weight, ribavirin dose is 1000mg
ü 75kg of body weight, ribavirin dose is 1200mg
Decompensated cirrhosis:
The recommended dose of Myhep dvir tablet is one tablet should be combined with weight based ribavirin.Drug caused side effects
Serious bradycardia during combination with amiodarone
HBV reactivation
Fatigue
Headache
Insomnia
Nausea
Pruritus
Asthenia
Anemia
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| myhep dvir tablet(Asthenia) |
Drug- drug interaction
Interaction with CYP3A inducers causes absence of action because of diminished concentration of Daclatasvir.
Myhep dvir tablet simultaneously utilize with CYP3A intense inhibitors, prompts raise the plasma concentration of Daclatasvir.
Interaction with warfarin prompts deliver changes in INR esteems and prothrombin time causes draining clutters.
Interaction with P-gp or BCRP powerful inhibitors causes expanded hazard identified with these substrates.
Interaction with protease inhibitors or NNRTI causes raising or exhausting the concentration of Daclatasvir individually.
Interaction with amiodarone, produces perilous bradycardia impacts.
Interaction with lipid bringing down operators causes expanded concentration of these specialists.
Interaction with any hostile to convulsants, against mycobacterials or herbal items causes expanded grouping of these medications prompts draining the sofosbuvir concentration.
Interaction with P-gp inducers causes loss of against viral action of Myhep dvir.
Safety measures
HBV reoccurrence:
This may occurs in HCV/HBV co contaminated patients, who are experienced HCV against viral treatment yet not get the HBV unfriendly to viral treatment.
Before occasion of HBV defilement;
Patients must be inside and out checked whether suspected with HBV pollution or not.
This condition is kept away from earlier by checking the HBsAg and threatening to HBc levels before begins the treatment using with Hepcinat in addition to.
After occasion of HBV ailment;
Hepatic limit test should be watched
Outfit organization related with HBV ailments.
Storage and handling
Myhep dvir tablet container should be stored by keeping at temperature of below 30oC
This container should be free from moisture, heat & light.
Missed dose
Myhep dvir tablet is a single dose therapy, if patient does not take the dose of Myhep dvir tablet must be consult with physician and follow the advice.
Otherwise the missed dose should be avoided and continue the regular schedule.
Over dosage
The maximum dose of Sofosbuvir is 1200mg, in case of over dosage condition;
Patients may provide with supportive measures
Alternative medicines should be recommended
Sofosbuvir over load is eliminated from the body by undergoing hemodialysis; 4 hours of process should remove nearly 18% of sofosbuvir content from the body
Daclatasvir is difficult to remove because it is highly bound to human plasma protein, but provide supportive measures to reduce the signs and symptoms.
FOR MORE INFORMATION:
EMAIL :millionhealthpharmaceuticals@gmail.com
MOBILE :+91-9940472902
WEBSITE URL:https://pillsbag.com/products/myhep-dvir
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