Buy Velpaclear Abbott Medicine uses, Side effects, Price, Cost India

VELPACLEAR

DESCRIPTION:




Drug profile:


Trade name: Velpaclear

Composition: Sofosbuvir & Velpatasvir

Strength of the components: 400mg & 100mg respectively

Manufacturer name: Abbott

Package: 28 tablets in a container

Classification: Anti-hepaciviral drug.



Drug Prescribing Information of Velpaclear tablets:


Velpaclear is used in following conditions like;

Patients suffered from compensated cirrhosis or without cirrhosis.

Patients with decompensated with long-lasting condition used in combination with ribavirin.

Velpaclear tablets are used in the conditions like hepatitis C viral infection in adolescents; HCV infection is caused by various genotypes like I, II, III, IV, V or VI.



Mechanism of Action of Velpaclear:


A Velpaclear tablet containing directly acting anti-viral agents such as sofosbuvir & Velpatasvir which expels their actions by undergoing some mechanism includes;

Sofosbuvir is an inhibitor of HCV NS5B RNA dependent RNA polymerase, an enzyme essential for viral production. Hence this inhibition causes depletion in viral proliferation.

Velpatasvir is an inhibitor of HCV NS5A is a pan genotype, NS5A is a protein required for HCV viral replication thus the inhibition leads to reduce the production of HCV virus in the human body.




Drug Called side effects:


Some effects may occur during the therapy of Velpaclear tablets;

Nausea

Insomnia

Asthenia

Elevate lipase level

Depression

Headache



velpaclear tablet
Velpaclear tablet(insomnia)




Overdosage:


No distinct antidote is applicable for overdosing of Velpaclear tablets; once the overdose occurs to confirm the presence of toxicity.



Treatment:


Check the crucial manifestations and give adjuvant measures.

The Hemodialysis is another method used in an overdose of Velpaclear tablets, can efficiently dispose of the dominant circulating metabolite of sofosbuvir, GS-331007 with eradicating ration of 53%.

Hence Velpatasvir is highly bound to the human plasma protein; it is not cleared by hemodialysis and gives incredible results.


velpaclear tablet(hemodialysis)

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